Chemistry has been available. As with the previous editions, the goal of this text is to
allow students to build on the foundation of introductory organic chemistry and attain
a level of knowledge and understanding that will permit them to comprehend much
of the material that appears in the contemporary chemical literature. There have been
major developments in organic chemistry in recent years, and these have had a major
influence in shaping this new edition to make it more useful to students, instructors,
and other readers.
The expanding application of computational chemistry is reflected by amplified
discussion of this area, especially density function theory (DFT) calculations in
Chapter 1. Examples of computational studies are included in subsequent chapters
that deal with specific structures, reactions and properties. Chapter 2 discusses the
principles of both configuration and conformation, which were previously treated in
two separate chapters. The current emphasis on enantioselectivity, including development
of many enantioselective catalysts, prompted the expansion of the section on
stereoselective reactions to include examples of enantioselective reactions. Chapter 3,
which covers the application of thermodynamics and kinetics to organic chemistry,
has been reorganized to place emphasis on structural effects on stability and reactivity.
This chapter lays the groundwork for later chapters by considering stability effects on
carbocations, carbanions, radicals, and carbonyl compounds.
Be the first to review “Advanced Organic Chemistry, Part A – Reactions and Synthesis, 5th Edition”